Biological and Biomedical Sciences

Checklists and Case Studies

Resources from Journals and Manufacturers

Literature Review

NIH suggests "applicants proposing to use cell lines could describe the method they plan to use to verify the identity and purity of the lines, which might include short tandem repeat (STR) profiling and mycoplasma testing." Below are some resources for writing an authentication plan and procedures for authenticating cell lines.

Guidelines and Resources from Professional and Non-Profit Organizations
Literature Review

Specific for Non-Human Cell Lines

  • Genome Editing - This collection of articles from the Nature Research journals provides an overview of current progress in developing targeted genome editing technologies. It also includes a selection of protocols that can be adapted
  • Enhancing Research Reproducibility is a collection of recommendations from Federation of American Societies for Experimental Biology (FASEB) that resulted from roundtable discussions. This document discusses overarching topics, mouse and other animal models, and antibodies