Jahar Battacharya: Effects of SARS-CoV-2 on Alveolar Epithelial Cells and Macrophages
Dr. Battacharya, in collaboration with Ira Tabas and Christine Garcia, is interested in understanding the basic mechanisms that the virus uses to infect critical cells in the pulmonary alveoli and cause acute respiratory distress syndrome. They plan to infect mice with a pseudovirus or the spike protein to evaluate the immunologic response, as well as the mechanistic processes that occur, such as the binding of ACE2 to enter the lung and disruption of macrophage and type 2 cell communication.
