Human Research Protection Office and IRBs

Frequently Used Services

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Human Research Policy Guide

HRPO/IRB Policies and guidelines, including the IRB Standard Operating Procedures, and a link to the Clinical Research Handbook provide a comprehensive overview of the policies and guidelines for conducting human subjects research at the University

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The Revised Common Rule

NEW! Find out about the revised federal regulations for human subjects research protection and how they affect you

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IRB Consultation Service

IRB consultations are offered at the Morningside, Manhattanville and Medical Center campuses. Check here for times and locations for walk-in consults - no appointment necessary

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Human Subjects Research Regulations & Ethical Principles

NEW! The recently revised federal regulations for human subjects research are now listed here, along with other relevant federal and state regulations, and ethical principles of human subjects research

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Protocol and Consent Form Resources

IRB reviews, creating and submitting a protocol, Consent Form templates and suggested language

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Maintain IRB Approval

All changes to the research protocol must be submitted for prospective IRB approval unless a change needs to be implemented immediately to remove or minimize an imminent harm to subjects

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Human Subjects Protection Training Program & Educational Resources

As a prerequisite for IRB approval, all human subjects researchers must complete CITI Human Subjects Protection and HIPAA Privacy training. Access training programs here.

IRB 101s and Monthly Investigator meetings (MIMs) are regularly scheduled information sessions. Slidedecks and materials from the meetings are posted here.


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Information for Research Participants

Find information about participating in research at the University

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Single IRB Review Process

NIH policy requires multi-site research studies to rely on single IRB (sIRB) review.  Check here HRPO guidance, resources, FAQs and the required form to submit for initiating an IRB reliance request 

Recent Announcements

July 25, 2019

IRB 101

The Columbia University Human Research Protection Office invites you to attend our upcoming "IRB 101" seminar. The intent of this session is to provide basic information about the history of human subjects protection, regulatory requirements, submission tips, and Rascal updates as they relate to the Human Research Protection Program and Institutional Review Board (IRB) review at Columbia.. Click here for the presentation slide deck.