Xiaoli Xiong - August 12, 2020

Video Category 1:

Xiaoli Xiong, PhD, Postdoctoral Research Scientist, Laboratory of Dr. John Briggs, MRC Laboratory of Molecular Biology (LMB), Cambridge, United Kingdom, "Engineering a closed thermostable SARS-CoV-2 Spike Protein"

Many therapies against COVID-19 use the S-protein of the virus as a docking point. Dr. Xiong presented his work which shows that the protein actually exists in two states: a retracted and a protruded one. This has influence on the storage at non-freezing temperatures, which Dr. Xiong is counteracting with stabilising crosslinking connections.