New Principal Investigators (PIs) and Laboratory

Welcome to Columbia University!

The role of Principal Investigator includes unique responsibilities for supporting the health and safety of laboratory personnel, in addition to their research goals. Environmental Health & Safety (EH&S) is the University’s primary resource to help ensure that laboratories are safe and compliant with all applicable local, state, and federal regulatory requirements. EH&S’ Research Safety program has a team of Safety Advisors whose role is to address safety-related questions and help get your laboratory started with safety and compliance preparations. Below you will find a list of actions to take to set your laboratory up for success and to maintain a safe and compliant research operation.

Complete in the first month:

  1. Complete the New Principal Investigator Questionnaire: This will ensure a smooth onboarding process and provide tailored resources for your research needs.
  2. Complete the Principal Investigator Research Safety Responsibilities  Training (TC6800) AND initial Laboratory Safety/Chemical Hygiene/Hazardous Waste Training (TC4951).
  3. EH&S Welcome Meeting: This short meeting will provide an overview of the services EH&S delivers and your lab’s safety responsibilities. Once the New Principal Investigator Questionnaire is completed, EH&S will reach out to you to set up a time.
  4. Complete Laboratory Assessment Tool and Chemical Hygiene Plan, or LATCH: Follow our guide or visual guide to complete this. This will allow you to add researchers to your roster (lab must complete lab safety training to be added to system), along with an emergency number.
  5. Meet with an EH&S Safety Advisor: This meeting focuses on answering any questions in completing the laboratory’s first LATCH and gives an opportunity to conduct a walkthrough of your space to address any questions. Please reach out to [email protected] to book an appointment.
  6. Meet with a Biosafety Officer ([email protected]) if your research involves recombinant DNA subject to the NIH guidelines, or potentially infectious material, including cultures, viral vectors or clinical specimens. A team member will also reach out to you after the completion of the questionnaire.
  7. Meet with a Radiation Officer ([email protected]) if your research involves radiation or working with radiation-producing equipment. A team member will also reach out to you after the completion of the questionnaire.
  8. Ensure all laboratory members complete the Initial Laboratory Safety/Chemical Hygiene/Hazardous Waste Training (TC4951) prior to starting laboratory work.
  9. Ensure that standardized operating procedures (SOP) are available to all laboratory members.
  10. Ensure all laboratory members complete topic-specific training depending on the lab’s operations. Applicable courses can be identified via the University’s Research Compliance Training Finder tool.
  11. Ensure that any employee members of the lab have completed applicable pre-placement medical surveillance and clearances.
  12. Update the laboratory door sign(s) with your name and the hazards found in the laboratory (door sign is based on campus, see below).

 

Laboratory Signage (by campus):

  1. Ensure that the laboratory has all the necessary Personal Protective Equipment (PPE), and spill kits.
     a. PPE: Laboratory coats can be rented from an approved vendor found here
     b. Gloves and protective eyewear can be purchased through a preferred laboratory supplier, such as Grainger or Fisher Scientific. 
     c. Spill Kits: Locations and requirements for laboratory spill kits depend on campus:
  • Morningside: Spill kits are managed by EH&S and located in the hallways with the exception of specialized spill kits (Mercury, HF, Formaldehyde).
  • JLG: Spill kits are managed by EH&S and are located under the sinks near the fume hoods with the exception of specialized spill kits (Mercury, HF, Formaldehyde).
  • CUIMC: The laboratory is responsible for purchasing and maintaining their spill kits.   
                   
  1. Ensure you and all laboratory members who are eligible apply to obtain an FDNY C-14 Certificate of Fitness. Information on applying can be found here.
  • If the laboratory will be working with flammable gas torches, the user may also need to obtain a G-60 Certificate of Fitness. Please contact EH&S for more information.
  • Post a copy of these cards in a central location in the lab.
     
  1. Ensure proper documentation is present: If the lab is installing a curtain in the lab, there must be proper documentation that the curtain is flame resistant (C-15 affidavit or manufacturer documentation). If the curtain does not have a tag proving IFR rating, please post documentation close to the curtains or at a central location to show on request.

Complete annually

  1. Renew your LATCH annually: This informs your laboratory of any changes in hazards and the PPE/emergency equipment available to them. Additionally, this provides an opportunity to update laboratory rosters, room rosters, and emergency contacts (used by Public Safety in the event of an emergency that involves your lab). Labs should update their LATCH accordingly when there are any changes to procedures resulting in new hazards.
  2. Ensure Laboratory Safety training is up to date for all staff (either through the Initial Laboratory Safety/Chemical Hygiene/Hazardous Waste Training (TC4951) OR Laboratory Safety, Chemical Hygiene, and Hazardous Waste Management Refresher Training (TC0950) for those who have completed the initial training).
  3. Ensure that the laboratory door sign is up to date.
  4. Ensure the laboratory continues to operate in a safe and compliant manner (See laboratory safety & compliance checklist below).

 

Laboratory Safety & Compliance Checklist.

Below is a printable checklist that the laboratory safety liaison or manager can review annually to help ensure the laboratory remains compliant with safety requirements. This checklist is designed to support routine evaluations, identify potential gaps, and promote a safe working environment for all laboratory personnel.

Checklist Printout

Laboratories that are departing or relocating must notify EH&S at [email protected] in advance to ensure a safe and compliant transition. When contacting EH&S, please include the planned departure or move date, whether any equipment requires EH&S clearance, and if chemical disposal is needed. If the laboratory is moving within the University, Facilities will not move or discard any equipment unless it has been cleared by EH&S. Any controlled substances must be properly redistributed, and all regulated medical waste (RMW) must be disposed of appropriately prior to departure. EH&S will conduct a walkthrough of the space, so laboratories should ensure the area is fully cleared for their next occupants. Below you will find important links to ensure your move is smooth:

  1. Checklist for Vacating a Laboratory:: The Vacating Lab Procedure serves as a checklist to guide laboratories as they prepare to relocate or depart a space. Not all sections may apply to every lab, so laboratories should review and follow only the sections relevant to their activities and materials. Completing the applicable steps helps ensure a safe, efficient, and compliant move.
  2. Laboratory Equipment and Room Clearance Form: Use this to request that EH&S clear equipment for moving and disposal. Facilities and some vendors will not move the equipment unless it has a clearance approval label on it. Equipment can be decontaminated by wiping it with a 10% bleach solution followed by 70% alcohol. Equipment that was used with radiation must be cleared by radiation safety team.
  3. Controlled Substance Reverse Distribution: EH&S cannot accept controlled substances for disposal. Expired or unwanted controlled substances must be handled by a reverse distributor for disposal. You can find answers to common Controlled Substance questions including information on reverse distribution (Q9).
  4. Chemical/Hazardous Waste Pickup Request Form: Any hazardous chemical (waste or stock bottles) that will be disposed of needs to be done so by EH&S. Ensure all containers are properly labeled and sealed for EH&S to pick up.